Did you know that laughing can help you lose weight? Everything you do burns some number of calories; therefore, you burn calories each time you laugh. Laughter also is good for your emotional and physical health, preparing you for a more rigorous exercise regimen, which will help you burn even more calories. How many calories can you burn laughing? A study conducted by researchers at Vanderbilt University revealed that you can burn as many as 50 calories when you laugh for 10 to 15 minutes, adding up to a weight loss of about 4 pounds in a year.